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Precision of HER2DX intra-laboratory. (A) Schematic outline of experimental design; (B) scatter plot revealing both intra- and inter-run variability across the three distinct HER2DX scores (i.e. relapse risk, pCR likelihood, and ERBB2 mRNA); (C) correlation matrix comparing runs from arm 1 and 2 with respect to the normalized gene expression of the 27 genes analyzed in the test. Correlation coefficients are shown.
Ctl, control; mRNA, messenger RNA; pCR, pathological complete response.
