Table 3.
Univariate and multivariate analysis of FASTKD2 in predicting lung cancer specific survival time.
| Category | Total number of people (n) | Single factor analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |||
| FASTKD2 | 503 | |||||
| High expression | 251 | Reference | ||||
| Low expression | 252 | 0.500 (0.350-0.714) | <0.001 | 0.562 (0.386-0.818) | 0.003 | |
| GENDER | 503 | |||||
| Male | 235 | Reference | ||||
| female sex | 268 | 0.910 (0.647-1.281) | 0.590 | |||
| AJCC staging | 503 | |||||
| Phase I | 280 | Reference | ||||
| Phase II | 118 | 2.217 (1.453-3.381) | <0.001 | 1.187 (0.582-2.418) | 0.637 | |
| Phase III | 79 | 3.008 (1.912-4.732) | <0.001 | 1.673 (0.573-4.884) | 0.347 | |
| Stage IV | 26 | 3.771 (2.044-6.956) | <0.001 | 8.033 (0.618-104.471) | 0.111 | |
| M | 503 | |||||
| M0 | 336 | Reference | ||||
| M1 | 25 | 2.250 (1.229-4.118) | 0.009 | 0.260 (0.021-3.284) | 0.298 | |
| MX | 142 | 0.929 (0.617-1.400) | 0.725 | 1.075 (0.702-1.645) | 0.741 | |
| N | 503 | |||||
| N3 | 14 | Reference | ||||
| N0 | 330 | 0.869 (0.273-2.767) | 0.812 | 1.519 (0.357-6.472) | 0.572 | |
| N1 | 90 | 1.939 (0.597-6.301) | 0.271 | 2.750 (0.609-12.417) | 0.188 | |
| N2 | 69 | 2.389 (0.724-7.880) | 0.153 | 2.358 (0.484-11.481) | 0.288 | |
| T | 503 | |||||
| T1 | 170 | Reference | ||||
| T2 | 266 | 1.585 (1.044-2.408) | 0.031 | 1.197 (0.773-1.853) | 0.420 | |
| T3 | 18 | 3.108 (1.426-6.771) | 0.004 | 1.359 (0.549-3.367) | 0.507 | |
| T4 | 49 | 2.765 (1.521-5.026) | <0.001 | 1.997 (0.956-4.170) | 0.066 | |
| Smoking | 503 | |||||
| yes | 421 | Reference | ||||
| no | 82 | 0.922 (0.583-1.458) | 0.728 | |||
| Age | 503 | |||||
| >65 | 256 | Reference | ||||
| ≤65 | 247 | 0.817 (0.580-1.151) | 0.248 | |||