Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Generation of NOD.Ifih1R mice. (A) Illustration of the location of the point mutation in Ifih1 at exon 15 as well as loxP sites using the CRISPR/Cas9 system. The point mutation is indicated in red (B) Sequence of the Ifih1 mutation. The point mutation is boxed. (C) Genotypes of mice (n=177) derived from the interbreeding of NOD.Ifih1NR/R heterozygous mice.
