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. 2024 Feb 29;15:1349601. doi: 10.3389/fimmu.2024.1349601

Figure 3.

Figure 3

NOD.Ifih1R increases the frequency of splenic CD69- CD8+ T cells. (A, B) CD8+ T cells in the spleen as (A) frequency of live cells and (B) total CD8+ T cell numbers in NOD.Ifih1NR/NR compared to NOD.Ifih1R/R mice (n=10 NOD.Ifih1NR/NR , n=12 NOD.Ifih1R/R ). (C) The splenic frequency of CD69+CD8+ T cells (CD3+CD8+CD69+) in 14-week-old NOD.Ifih1NR/NR compared to NOD.Ifih1R/R mice (n=10 NOD.Ifih1NR/NR , n=12 NOD.Ifih1R/R ). (D) Representative gating of CD69+ CD8+ T cells (CD3+CD8+CD69+) from 14-week-old NOD.Ifih1NR/NR and NOD.Ifih1R/R mice by flow cytometry. P values were determined using student’s unpaired t tests. All data are mean ± SEM.