Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Feb 29;15:1349601. doi: 10.3389/fimmu.2024.1349601

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2024 Stock, Gonzalez Paredes, de Almeida, Kosanke, Chetlur, Budde, Wakenight, Zwingman, Rosen, Allenspach, Millen, Buckner, Rawlings and Gorman

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

NOD.Ifih1^R increases the frequency of CD69 on CD8⁺ T cells in non-draining female lymph nodes. (A, B) CD8⁺ T cells in the lymph nodes (LN) as (A) frequency of live cells and (B) total CD8⁺ T cell numbers in NOD.Ifih1^NR/NR compared to NOD.Ifih1^R/R mice (n=10 NOD.Ifih1^NR/NR , n=12 NOD.Ifih1^R/R ). (C, D) The frequency of CD69⁺ CD8⁺ T cells (CD3⁺CD8⁺CD69⁺) from lymph nodes of (C) all 14-week-old NOD.Ifih1^NR/NR compared to NOD.Ifih1^R/R mice (n=10 NOD.Ifih1^NR/NR , n=12 NOD.Ifih1^R/R ) and (D) female NOD.Ifih1^NR/NR compared to NOD.Ifih1^R/R mice (n=8 NOD.Ifih1^NR/NR , n=9 NOD.Ifih1^R/R ). (E) Representative gating of CD69⁺ CD8⁺ T cells (CD3⁺CD8⁺CD69⁺) from lymph nodes of 14-week-old female NOD.Ifih1^NR/NR and NOD.Ifih1^R/R mice by flow cytometry.