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. 2024 Feb 29;15:1349601. doi: 10.3389/fimmu.2024.1349601

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Copyright © 2024 Stock, Gonzalez Paredes, de Almeida, Kosanke, Chetlur, Budde, Wakenight, Zwingman, Rosen, Allenspach, Millen, Buckner, Rawlings and Gorman

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NOD.Ifih1^R accelerates diabetes incidence in females. (A-C) Diabetes incidence in (A) total mice (n=30 per genotype), (B) females only (n=14 NOD.Ifih1^NR/NR , n=15 NOD.Ifih1^R/R ), and (C) males only (n=16 NOD.Ifih1^NR/NR , n=15 NOD.Ifih1^R/R ), and displayed using Kaplan Meier survival curves. P values for diabetes incidence in (A-C) were determined by performing Gehan-Breslow-Wilcoxon tests.