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. 2024 Feb 29;11:1305431. doi: 10.3389/fmed.2024.1305431

TABLE 1.

Animal models of gouty nephropathy.

Animals species Name Species Modeling method Disease cycle References
Poultry White Henleys Birds, Pheasant High protein diet, 19.11%, p.o 70 days (61)
Proto chickens Birds, Pheasant Cisplatin, 3.5 mg/mg, i.p 48 h (62)
Broiler Birds, Pheasant Inosine food, 6.7 mol/kg, p.o 21 days (63)
Difacia strain quail Birds, Pheasant Yeast extract powder, p.o 60 days (64)
Longcheng quail Birds, Pheasant Lard stearin + cholesterol, 14 + 1%, p.o 14 days (65)
French quail Birds, Pheasant Yeast extract + fructose, 10%, p.o 30 days (66)
Red-tailed hawk Ornithischia, Falconiformes, subfamily Buzzard High purine food, p.o 72 h (67)
Mammals Mice Mammalia, Rodentia Muridae Oxybate + yeast, 300 mg/kg, i.p 8 days (68)
Rats Mammalia, Rodentia Muridae Adenine, 300 mg/kg, p.o 21 days (69)
Mice Mammalia, Rodentia Muridae Adenine +potassium oxybate, 100 + 500 mg/kg 21 days (70)
Mice Mammalia, Rodentia Muridae Fructose + fat + cholesterol, 0.15 + 43% + 15, p.o 16 weeks (71)
Mice Mammalia, Rodentia Muridae Adenine, 0.15%, p.o 24 weeks (72)
Mice Mammalia, Rodentia Muridae Rodentia Knockout uric acid oxidase gene (73)
Rats Mammalia, Rodentia Muridae Uric acid, 250 mg/kg, i.p 28 days (74)
Albino rabbits Mammalia, Rutaceae Fructose Fructose, 1 g/kg, p.o 42 days (75)
Swedish long white pig Mammalia, Diptera, Suidae Uric acid + inosine + fructose, 40 mg/ml, i.p + 20 + 0.9%, p.o 14 days (76)
Dalmatian Mammalia, Carnivora Canidae SLC2A9 gene sequence mutation (77)
Other classes Tree shrews Zebrafish Mammalia, Primate family Tree Shrew Scleractinian, Cyprinidae Oxonate suspension, 80 mg/kg, i.p Potassium oxybate, 125 μg/ml 12, 24 h (79, 81)