Table 1.
Cohort characteristics for HBS, MGB, Optum, and Fox Insights cohorts
| HBS | Fox Insight | MGB | Optum Claims-EHR | |
|---|---|---|---|---|
| Total population with PD | 935 | 36,660 | 22,949 | 157,475b |
| Population with data since initial PD diagnosis | 935 | 36,660 | 13,257 | 157,475b |
| Percentage of the population with data from initial PD diagnosis who are Male | 67.0% | 55.8% | 57.8% | 56.7% |
| Mean age at diagnosis (years) [25% and 75%] | 62.5 [56.0–70.0] | 60.3 [53.6–61.3] | 72.9 [66.5–81.2] | 72.1 [66.0–80.0] |
| Mean years from diagnosis to study enrollment [25%, 75%] | 3.7 [0.0–5.0] | 3.5 [1.2-7.5] | NA | NA |
| Mean initial H&Y stage if recorded within 1 year of diagnosis (MGB) or at enrollment (HBS) [25%, 50%, 75%] |
2.1 [2, 2, 2.5] n = 853 |
NA |
2.3 [2, 2, 3] n = 1071 |
NA |
| Mean length of follow-up from disease diagnosis (years) [25%, 75% percentile] | 6.2 [2.0–9.0] | 1 [0–1.0]a | 3.8 [0.7–5.6] | 3.1 [0.6–4.9]c |
aYears enrolled within Fox Insight. Due to the survey nature of the data source, historical data are available for certain information.
bSubjects at MGB and Optum were only included if they had at least two years of data coverage prior to initial PD diagnosis. This quiescence period was designed to filter for de novo diagnoses.