Table 3.
Effect of CrE ingestion by obese rats on AFI, AWI, pancreatic activity of antioxidant enzymes (SOD, CAT and GPX) and metabolic catabolism enzymes (HK, PK and 6PD and carbohydrate metabolism (G6P and FBP) in the liver. Our results clearly show that CrE stimulates glucose degradation and inhibits monossaccharide biosynthesis. Statistical analyses as given as: *P < 0.05 significant differences compared to controls; @P < 0.05 significant differences compared to diabetic rats; #P < 0.05 significant differences compared to diabetic rats treated with CPC100. &P < 0.05 significant differences compared to diabetic rats treated with CPC200.
| Con | O | D-CrE100 | D-CrE200 | D-Orl | |
|---|---|---|---|---|---|
| AFI | 17.3 ± 1.5 | 21.9 ± 1.6* | 19.3 ± 1*@ | 18.3 ± 1.3 | 17.9 ± 2.1*@ |
| AWI | 18.5 ± 1.5 | 23.9 ± 2.1* | 21.7 ± 1.7*@ | 20.3 ± 1.4*@ | 21.7 ± 1.8*@ |
| SOD | 1.35 ± 0.21 | 0.73 ± 0.13*# | 0.97 ± 0.14#@ | 1.23 ± 0.17#@ | 0.93 ± 0.11*#@ |
| CAT | 31.9 ± 3.9 | 11.2 ± 0. 97**# | 21.9 ± 2.3#@ | 26.3 ± 3.1#@ | 23.9 ± 1.9#@$ |
| GPX | 2.19 ± 0.21 | 0.93 ± 0.1*# | 1.56 ± 0.19* | 1.98 ± 0.39* | 1.32 ± 0.19*#@ |
| HK | 251 ± 29 | 137 ± 17* | 197 ± 31*@ | 209 ± 23*@ | 129 ± 17*@ |
| PK | 201 ± 31 | 104 ± 9* | 163 ± 19*@ | 173 ± 35*@ | 141 ± 19*@ |
| G6PD | 497 ± 39 | 207 ± 29* | 421 ± 47*@ | 477 ± 29*@ | 397 ± 53*@ |
| G6P | 697 ± 29 | 1537 ± 86* | 1147 ± 81*@ | 789 ± 47*@ | 1137 ± 65*@# |
| FBP | 349 ± 25 | 803 ± 51* | 549 ± 49*@ | 402 ± 63*@ | 671 ± 59*@# |