FIG. 7.

Sequence analysis of S1 nuclease products derived from the DR_R-DR_L genome junction. The small DNA fragment produced upon digestion of pCO with S1 and XmnI was molecularly cloned, and a total of seven such clones were then sequenced, in order to map precisely the site of S1 nuclease cleavage. The sequence of pC62 (used to create pCO) is shown, together with the positions of consensus DNA motifs (pac1 and pac2). Arrows indicate the sites of S1 nuclease-mediated cleavage for the clones that were sequenced (the number 3 means that 3 clones had an identical cleavage site).