Table 1.

Top five highest and lowest curvature edges at ${\tau }_{\mathit{crit}}$.

Gene A	Gene B	${\overline{\kappa }}_{\mathit{crit}}$
FRK	ARMC8	0.804
CDC27	CBX8	0.791
CD3D	CD274	0.777
CUL1	PSMA4	0.768
CLTC1	SYNJ2	0.764
LDLR	APOB	− 0.921
MAPK10	TP53	− 0.842
CDKN1A	ABL1	− 0.826
LDLR	APOA1	− 0.822
AP2S1	SH3GL3	− 0.796