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. 2024 Mar 13;15:2254. doi: 10.1038/s41467-024-46490-7

Fig. 2. Replication kinetics of SARS-CoV-2 variants in Vero E6, Vero E6 TMP-1 and -2 and IGROV-1 cells.

Fig. 2

a Cells were infected with the indicated variants, at 3 × 10–2 infectious units per cell. Cells were stained with a pan-coronavirus anti-N antibody at days 1–4 pi. The N-positive areas were plotted on the graph. Each curve represents an independent experiment. b Comparison of the effect of E-64d and SB412515 against different variants. IGROV-1 cells were pre-incubated 2 h with serial dilutions of E-64d or SB412515 (30–1.7 × 10–4 µM) and infected with D614G, XBB.1.5, EG.5.1.3, or BA.2.86.1. The percentage of inhibition is represented. Data are mean ± s.d. of 3 independent experiments. Source data are provided as a Source Data file.