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. 2024 Mar 1;116(1):32–45. doi: 10.32074/1591-951X-926

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Figure 4. — MMR/MSI testing and MLH1 promoter hypermethylation assessment inEC. (A) Percentage of samples tested for MMR and/or MSI in the different European countries in 2020. N: total number of samples by countries.(B) Percentage of samples tested for MMR and/or MSI in Italy and Switzerland during the first quarter of 2021. N: total number of samples by countries. (C) Strategy used in case of negative MLH-1/PMS-2 expression. N: total number of laboratories testing for MMR. (D) Molecular methods used to analyze the hypermethylation status of the MLH-1 promoter. N: total number of labs testing the hypermethylation of the MLH-1 promoter.