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. 2024 Feb 27;9(10):11836–11847. doi: 10.1021/acsomega.3c09427

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© 2024 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Integrated analysis of target genes and compound interactions. (A) Venn plot: This panel displays a Venn plot showcasing the common genes shared between compound-related and disease-related targets, providing insights into potential overlaps. (B) Compound–Target Network: In this subfigure, nodes represent compounds and their associated proteins. Node size reflects the degree of connectivity, emphasizing key interactions within the network. (C) Top 10 Hub genes: This panel highlights the top 10 genes ranked based on the degree algorithm, underlining their significance in the network. (D) Hub gene degrees: Shown as a bar plot, this subfigure represents the degree of connectivity for each hub gene, providing a visual perspective on their importance within the network.