Table 2.

Multivariable model evaluating risk of death among the entire patient cohort.

Feature	Hazard ratio	95% Confidence ratio	P Value
Cytoreductive nephrectomy	0.33	0.24–0.45	<0.0001
Histology
Clear cell	1.0 (reference)	-	-
Non-clear cell	2.08	1.37–3.15	0.001
Other/Unknown	1.61	1.08–2.39	0.02
Total metastatic sites
Only 1	1.0 (reference)	-	-
2 or more	1.09	0.81–1.47	0.6
Age at metastatic diagnosis	1.00	0.99–1.02	0.7
IMDC risk score
Favorable	1.0 (reference)	-	-
Intermediate	1.24	0.65–2.38	0.5
Poor	2.28	1.13–4.61	0.02
ICI utilization
First line	1.0 (reference)
Second line or later	1.03	0.7–1.53	0.9