Table 4.
Multivariable analysis evaluating the risk of death among subgroup of patients who received first-line ICI therapy.
| Feature | Hazard ratio | 95% Confidence ratio | P Value |
|---|---|---|---|
| Cytoreductive nephrectomy | 0.19 | 0.09–0.43 | <0.0001 |
| Histology | |||
| Clear cell | 1.0 (reference) | - | - |
| Non-clear cell | 3.18 | 0.65–15.5 | 0.15 |
| Other/Unknown | 1.57 | 0.73–3.38 | 0.25 |
| Total metastatic sites | |||
| Only 1 | 1.0 (reference) | - | - |
| 2 or more | 1.84 | 0.87–3.90 | 0.11 |
| Age at metastatic diagnosis | 1.00 | 0.97–1.04 | 0.8 |
| IMDC risk score | |||
| Favorable | 1.0 (reference) | - | - |
| Intermediate | 1.91 | 0.24–15.4 | 0.5 |
| Poor | 1.86 | 0.23–15.0 | 0.6 |