Figure 6.

Model of the 5′ UTR region of SARS-CoV-2 genomic RNA built by HCG. (A) Ensemble overview. (B) and (C) show two representatives of extended and compact conformations, respectively, with more detail. Structures of the five stem-loop regions drawn at random from MD trajectories⁵³ are shown in red. The connecting single-stranded RNA is shown in blue. The structures are shown with atomic detail. Hydrogen atoms are omitted for clarity. The backbone atoms are shown in a cartoon representation except for the last stem-loop at the 3′ end, which is highlighted as a surface. The full-length structure shown here covers 233 nucleotides.