Table 2.

Crude incidences (95% CI) of overall dementia disaggregated by sex, age, and exposure groups

Sex	Age	Whole population	Exposure groups* (risk at baseline) n (%); mean [sd]
			Low CVR	Low-intermediate CVR	High-intermediate CVR	High CVR	Previous vascular disease
Women	50,55	0.39 (0.36–0.43)	0.37 (0.34–0.40)	0.62 (0.44–0.88)	1.17 (0.68–2.01)	1.70 (0.81–3.56)	0.96 (0.60–1.54)
	55,60	1.08 (1.03–1.14)	1.00 (0.94–1.05)	1.44 (1.24–1.67)	1.79 (1.38–2.33)	2.33 (1.66–3.26)	2.28 (1.81–2.89)
	60,65	3.16 (3.07–3.24)	2.93 (2.84–3.02)	3.62 (3.35–3.92)	4.15 (3.62–4.75)	4.90 (4.14–5.80)	5.33 (4.74–5.99)
	65,70	7.22 (7.07–7.37)	6.87 (6.71–7.03)	7.77 (7.32–8.23)	8.86 (8.03–9.78)	8.28 (7.19–9.54)	9.88 (9.14–10.68)
	70,75	14.51 (14.29–14.73)	14.10 (13.87–14.34)	14.79 (14.06—15.55)	15.06 (13.68–16.59)	16.27 (14.10–18.77)	18.15 (17.29–19.06)
	All	4.79 (4.74–4.84)	4.37 (4.32–4.42)	5.86 (5.65–6.08)	6.51 (6.10–6.94)	6.92 (6.34–7.57)	10.30 (9.91–10.70)
Men	50,55	0.45 (0.41–0.49)	0.41 (0.37–0.46)	0.52 (0.41–0.67)	0.40 (0.23–0.71)	0.62 (0.30–1.30)	0.80 (0.57–1.13)
	55,60	1.07 (1.01–1.14)	0.93 (0.86–1.01)	1.05 (0.91–1.22)	1.10 (0.87–1.40)	1.64 (1.26–2.14)	2.11 (1.79–2.49)
	60,65	2.79 (2.68–2.89)	2.44 (2.30–2.58)	2.80 (2.60–3.02)	2.96 (2.65–3.31)	3.05 (2.68–3.48)	3.96 (3.60–4.36)
	65,70	5.84 (5.68–6.01)	5.37 (5.10–5.66)	5.37 (5.07–5.69)	5.51 (5.11–5.95)	6.39 (5.93–6.89)	7.70 (7.20–8.23)
	70,75	11.88 (11.64–12.14)	11.39 (10.83–11.98)	10.99 (10.51–11.49)	11.15 (10.61–11.73)	11.71 (11.19–12.26)	14.72 (14.05–15.41)
	All	3.95 (3.89–4.01)	2.22 (2.15–2.29)	4.29 (4.13–4.46)	5.72 (5.50–5.96)	7.33 (7.05–7.61)	7.27 (7.03–7.52)

^*Exposure groups based on cardiovascular risk (CVR) at baseline: low (Framingham-REGICOR < 5%), low-intermediate (5% ≤ Framingham-REGICOR < 7.5%), high-intermediate (7.5% ≤ Framingham-REGICOR < 10%), high (Framingham-REGICOR ≥ 10%), and patients with history of vascular disease before the baseline