. 1998 Jan;72(1):396–404. doi: 10.1128/jvi.72.1.396-404.1998

TABLE 2.

Inhibition of M-tropic viruses by CC-chemokines^a

Virus	Subtype	RANTES		MIP-1α		MIP-1β		Mix
Virus	Subtype	ID₉₀	ID₅₀	ID₉₀	ID₅₀	ID₉₀	ID₅₀	ID₉₀	ID₅₀
92RW026	A	175	53.8	>456*	177	272	61.4	201	94.5
DJ258	A	66	28.7	281.9	142	339	55.9	54.7	<12.2†
JRFL	B	107	32.0	>499*	236	439	156	152	75.5
JRCSF	B	223	99.2	>485*	369	463	295	122	59.3
SF162	B	413	50.8	>500	>500	>500	>500*	>500*	296
92US657	B	359	97.9	>348*	281*	467	86.8	>294*	15.5
DJ259	C	27.3	11.4	255	27.5†	403	69.3	27	13.8
94ZW103	C	74.2	42.0	303	79.4	297	153	198	54.0
94ZW109	C	88.9	<13.9†	460	205	381*	<192†	226	15.1
94KE102	D	39.9	16.3	376	60.1	190	101	83.4	18.4
94KE103	D	28.9	19.7	91.3	19.6	27.7	5.9	24	9.6
CM235	E	227	70.6	>500	>500	>500	>500*	>500*	313
92TH001	E	74.6	51.2	>500	168	275.2	176	118	87.5
BZ162	F	256	49.2	>500	455	246.2	184	408	108
R1	F	24.6	<1.95†	376	<1.95	310.5	<1.95	255	<1.95

The median ID₅₀s and ID₉₀s (in nanograms per milliliter) for the CC chemokines RANTES, MIP-1α, and MIP-1β, and a 1:1:1 mixture of all three (Mix) against each M-tropic isolate are recorded. A value of >500 indicates that 50 or 90% inhibition was not achieved at a CC chemokine concentration of 500 ng/ml (the highest tested) in any experiment. A value of <1.95 indicates that 50 or 90% inhibition was always achieved at a CC chemokine concentration of 1.95 ng/ml (the lowest tested). Some median values are marked with an asterisk or dagger because in some of several experiments with this virus and CC chemokine combination, the ID₅₀ or ID₉₀ recorded was <1.95 ng/ml or >500 ng/ml. For the purposes of calculating the medians of multiple determinations, the off-scale values were set at 1.95 or 500, and the resulting median is considered a lower or upper limit, respectively. The “<” or “>” symbols by these values also indicate this.