Fig. 1.

Clusters of co-expressed genes associated with epigenetic variability and chromosomal instability in PRAD. In brief, 13 clusters of co-expression genes were generated from TCGA PRAD datasets using WGCNA [16]. To identify clusters associated with epigenetic variability and chromosomal instability, GSEA, regression analysis between eigengene of cluster and CpG-site methylation or chromosomal instability index was performed. DE differential expression, DM differential methylation, CIN chromosomal instability index