Table 2.
Primary and secondary outcomes in patients: pre vs. post intervention (DT + and DT combined)
| T0 | T1 | Comparison (T1-T0) | Statistics | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Subgroups | Measures | N | Mean | SD | N | Mean | SD | Mean difference (SE) | 95% CI | p-value |
| DT + DT combined | Hastened Death | 28 | 2.07 | 2.09 | 28 | 1.71 | 1.96 | -0.36 (0.36) | -1.10; 0.38 | 0.33 |
| HADS total | 28 | 17.04 | 6.09 | 28 | 16.96 | 7.35 | -0.07 (0.62) | -1.34; 1.20 | 0.91 | |
| HADS anxiety | 28 | 8.50 | 3.36 | 28 | 8.29 | 4.23 | -0.21 (0.40) | -1.03; 0.60 | 0.59 | |
| HADS depression | 28 | 8.54 | 3.64 | 28 | 8.68 | 4.33 | 0.14 (0.44) | -0.75; 1.04 | 0.75 | |
| DTherm | 28 | 5.79 | 2.54 | 28 | 6.21 | 2.32 | 0.43 (0.46) | -0.51; 1.36 | 0.36 | |
| FACIT-Pal-14 | 27 | 27.67 | 5.88 | 27 | 33.81 | 7.84 | 6.15 (1.86) | 2.33; 9.96 | 0.01 | |
| FACIT-SP-12 | 27 | 24.42 | 4.44 | 27 | 25.54 | 9.50 | 0.12 (1.58) | -3.12; 3.37 | 0.94 | |
| PDI tot | 27 | 57.70 | 13.35 | 27 | 54.63 | 16.13 | -3.07 (3.01) | -9.26; 3.12 | 0.32 | |
| PDI Symp distress | 27 | 2.44 | 0.66 | 27 | 240 | 0.84 | -0.04 (0.14) | -0.33; 0.25 | 0.80 | |
| PDI Exi distress | 27 | 2.59 | 0.70 | 27 | 2.25 | 0.85 | -0.33 (0.17) | -0.68; 0.02 | 0.06 | |
| PDI Dependency | 27 | 2.53 | 0.85 | 27 | 2.44 | 0.85 | -0.10 (0.15) | -0.40; 0.21 | 0.52 | |
| PDI Peace of Mind | 27 | 1.88 | 0.73 | 27 | 1.77 | 0.70 | -0.11 (0.18) | -0.48; 0.27 | 0.57 | |
| PDI Social Support | 27 | 1.47 | 0.75 | 27 | 1.44 | 0.73 | -0.03 (0.13) | -0.30; 0.30 | 0.85 | |
| PRISM | 27 | 2.70 | 2.00 | 27 | 3.11 | 2.14 | 0.41 (0.23) | -0.05; 0.87 | 0.08 | |
| SPC | Hastened Death | 13 | 2.00 | 1.78 | 13 | 1.92 | 1.98 | -0.08 (0.40) | -0.95; 0.79 | 0.85 |
| HADS total | 14 | 13.64 | 4.09 | 14 | 17.79 | 9.72 | 4.14 (2.61) | -1.501; 9.79 | 0.14 | |
| HADS anxiety | 14 | 6.14 | 2.60 | 14 | 8.36 | 4.81 | 2.21 (1.19) | -0.36; 4.79 | 0.09 | |
| HADS depression | 14 | 7.50 | 2.68 | 41 | 9.43 | 5.64 | 1.93 (1.53) | -1.37; 5.23 | 0.23 | |
| DTherm | 14 | 6.21 | 2.19 | 14 | 6.00 | 2.48 | -0.21 (0.48) | -1.26; 0.83 | 0.66 | |
| FACIT-Pal-14 | 11 | 30.82 | 5.33 | 11 | 30.90 | 9.47 | 0.08 (3.76) | -8.29; 8.46 | 0.98 | |
| FACIT-SP-12 | 11 | 28.27 | 4.45 | 11 | 27.55 | 7.50 | -0.73 (2.65) | -6.62; 5.17 | 0.79 | |
| PDI tot | 11 | 52.36 | 14.45 | 11 | 54.55 | 17.43 | 2.18 (2.81) | -4.07; 8.43 | 0.46 | |
| PDI Symp distress | 11 | 2.28 | 0.61 | 11 | 2.43 | 0.77 | 0.15 (0.21) | -0.31; 0.61 | 0.48 | |
| PDI Exi distress | 11 | 2.20 | 0.71 | 11 | 2.31 | 0.79 | 0.12 (0.11) | -0.13; 0.37 | 0.31 | |
| PDI Dependency | 11 | 2.25 | 0.87 | 11 | 2.22 | 0.83 | -0.04 (0.13) | -0.32; 0.24 | 0.78 | |
| PDI Peace of Mind | 11 | 1.79 | 0.76 | 11 | 1.88 | 0.92 | 0.09 (0.23) | -0.43; 0.61 | 0.71 | |
| PDI Social Support | 11 | 1.42 | 0.54 | 11 | 1.48 | 0.72 | 0.06 (0.18) | -0.34; 0.46 | 0.74 | |
| PRISM | 13 | 4.25 | 2.68 | 13 | 2.79 | 1.91 | -1.46 (0.84) | -3.30; 0.37 | 0.11 | |
Abbreviations: DT + Dignity Therapy Patients and Partners, DT Dignity Therapy with Patients, SPC standard palliative care, SD standard deviation, HADS Hospital Anxiety and Depression Scale, DTherm Distress Thermometer, FACIT-Pal-14 FACIT-Palliative Care, FACIT-SP-12 FACIT Spiritual Well-Being, PDI Patient Dignity Inventory, PRISM Pictorial Representation of Illness and Self Measure