TABLE 2.
Association of Lack of Circumcision and HIV Infection and STD Diagnoses Over 6924 Clinic Visits by 3828 MSM Stratified by Reported Anal Sex Role in the Preceding Year, Public Health–Seattle and King County STD Clinic, 2001–2006
| Uncircumcised (n = 1081) | Circumcised (n = 5843) | Crude OR (95% CI) | Adjusted OR* (95% CI) | |
|---|---|---|---|---|
| All men reporting anal sex in the past year | ||||
| New HIV+ | 15/449 (3.3) | 59/2324 (2.5) | 1.33 (0.74, 2.37) | 0.90 (0.57, 1.40) |
| Ever HIV+ | 166/823 (20.2) | 957/4301 (22.3) | 0.94 (0.85, 1.03) | 0.90 (0.82, 1.00) |
| HSV-2+ | 50/372 (13.4) | 312/2015 (15.5) | 0.85 (0.62, 1,17) | 0.82 (0.58, 1.14) |
| Syphilis† | 5/884 (0.57) | 43/4689 (0.92) | 0.60 (0.24, 1.53) | 0.50 (0.18, 1.35) |
| Urethral GC | 96/815 (11.8) | 551/4226 (13.0) | 0.99 (0.78, 1.26) | 0.97 (0.75, 1.26) |
| Urethral Chlamydia | 61/962 (6.3) | 332/5159 (6.4) | 1.00 (0.75, 1.36) | 0.98 (0.71, 1.35) |
| Men practicing only insertive anal sex in the past year (1595 visits) | ||||
| New HIV+ | 2/82 (2.4) | 10/502 (2.0)) | 1.23 (0.26, 5.87) | 0.92 (0.17, 4.97) |
| Ever HIV+ | 25/165 (15.2) | 145/923 (15.7) | 0.96 (0.53, 1.74) | 0.88 (0.46, 1.70) |
| HSV-2+ | 9/87 (10.3) | 68/448 (15.2) | 0.63 (0.27, 1.50) | 0.66 (0.27, 1.63) |
| Syphilis† | 0/184 | 5/1059 (0.5) | — | — |
| Urethral GC | 20/185 (10.8) | 191/1013 (18.9) | 0.67 (0.34, 1.33) | 0.75 (0.37, 1.51) |
| Urethral Chlamydia | 16/214 (7.5) | 105/1221 (8.6) | 1.30 (0.66, 2.60) | 1.12 (0.54, 2.32) |
| Men practicing both insertive and receptive anal sex in the past year (4611 visits) | ||||
| New HIV+ | 10/305 (3.3) | 45/1618 (2.8) | 1.19 (0.59, 2.39) | 1.07 (0.53, 2.15) |
| Ever HIV+ | 124/558 (23.7) | 697/2937 (22.2) | 0.96 (0.88, 1.04) | 0.93 (0.85, 1.02) |
| HSV-2+ | 34/237 (14.4) | 205/1351 (15.2) | 0.94 (0.64, 1.38) | 0.95 (0.63, 1.43) |
| Syphilis† | 4/584 (0.7) | 30/3152 (1.0) | 0.69 (0.24, 1.99) | 0.62 (0.20, 1.96) |
| Urethral GC | 73/539 (13.5) | 347/2849 (12.2) | 1.17 (0.88, 1.56) | 1.14 (0.84, 1.55) |
| Urethral Chlamydia | 42/623 (6.7) | 216/3455 (6.3) | 1.08 (0.76, 1.55) | 1.13 (0.76, 1.68) |
| Men reporting only receptive anal sex in the past year (718 visits) | ||||
| New HIV+ | 3/62 (4.8) | 4/204 (2.0) | 2.53 (0.56, 11.56) | 2.34 (0.34, 16.29) |
| Ever HIV+ | 17/100 (17.0) | 115/441 (26.1) | 0.58 (0.32, 1.07) | 0.68 (0.43, 1.06) |
| HSV-2+ | 7/48 (14.6) | 39/216 (18.1) | 0.76 (0.32, 1.78) | 0.69 (0.27, 1.78) |
| Syphilis† | 1/116 (0.9) | 8/478 (1.7) | 0.58 (0.09, 3.77) | 0.38 (0.05, 2.83) |
| Urethral GC | 3/91 (3.3) | 13/364 (3.6) | 1.14 (0.31, 4.11) | 0.82 (0.22, 2.97) |
| Urethral Chlamydia | 3/125 (2.4) | 11/483 (2.3) | 1.05 (0.29, 3.82) | 0.79 (0.19, 3.24) |
*
Adjusted for age and race/ethnicity.
†
RPR ≥1:8.