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. 2024 Feb 29;18(10):7618–7632. doi: 10.1021/acsnano.4c00550

Figure 1.

Figure 1

Synthesis and characterization of AnCHNPs. (a) Schematic illustration showing the steps of nanoparticle synthesis, surface coating, and antibody conjugation. (b) SEM images of CHNPs and SCHNPs. Scale bars, 200 nm. (c) TEM images of CHNPs (left) and SCHNPs (right). Scale bars: 200 nm (black) and 100 nm (white), respectively. (d) EDS elemental mapping shows the core/shell structure of SCHNPs. Scale bar, 250 nm. (e) XRD spectra of SCHNPs, CHNPs, and the Ca(OH)2 reference. (f) EDS spectra of SCHNPs. (g) DLS spectra of CHNPs, PCHNPs, and AnCHNPs, tested in water. (h) Zeta potentials of CHNPs, SCHNPs, PCHNPs, and AnCHNPs, measured in PBS (n = 3). (i) AnCHNPs are stable in PBS after incubation for 24 h.