Table 2. Pooled predictive parameters of the Mini-Cog based on cognitive status and healthcare settings.

Cognitive status
Predictive parameters	Dementia	MCI	CI
	(6 studies, n = 4,772) [26,28,31,35–37]	(2 studies, n = 270) [33,34]	(8 studies, n = 2,152) [11,27–30,32,38]
Prevalence	0.25 (0.24–0.26)	0.38 (0.32–0.44)	0.34 (0.32–0.36)
Sensitivity	0.76 (0.73–0.78)	0.84 (0.75–0.90)	0.67 (0.63–0.70)
Specificity	0.83 (0.82–0.84)	0.79 (0.72–0.85)	0.83 (0.81–0.85)
PPV	0.60 (0.58–0.63)	0.71 (0.62–0.79)	0.68 (0.64–0.71)
NPV	0.91 (0.90–0.92)	0.89 (0.83–0.94)	0.83 (0.81–0.85)
DOR	15.67 (13.37–18.38)	20.43 (10.66–39.15)	10.98 (4.44–27.2)
SROC	AUC = 0.85 (0.73–0.90)	AUC = NA	AUC = 0.84 (0.75–0.87)
Healthcare settings
Predictive parameters	Primary/community care	Secondary care/ memory clinic	Emergency department
	(8 studies, n = 5,620) [11,26–31]	(7 studies, n = 1,499) [32–37]	(1 study, n = 75) [38]
Prevalence	0.20 (0.19–0.22)	0.58 (0.55–0.60)	0.21
Sensitivity	0.73 (0.71–0.76)	0.73 (0.70–0.77)	0.75 (0.48–0.93)
Specificity	0.84 (0.83–0.85)	0.76 (0.73–0.80)	0.85 (0.73–0.93)
PPV	0.54 (0.51–0.56)	0.81 (0.78–0.83)	NA
NPV	0.92 (0.92–0.93)	0.67 (0.64–0.71)	NA
DOR	14.20 (12.19–16.55)	8.59 (6.78–10.88)	NA
SROC	AUC = 0.84 (0.76–0.89)	AUC = 0.83 (0.74–0.89)	NA

Abbreviations: AUC, area under the curve; CI, cognitive impairment; DOR, diagnostic odds ratio; MCI, mild cognitive impairment; NA, not available; NPV, negative predictive value; PPV, positive predictive value; SROC, summary receiver operating characteristic. Studies that detect cognitive impairment include patients with MCI or dementia. Pooled predictive parameters based on healthcare setting detect cognitive impairment (defined as either dementia or MCI).