FIG. 3.

CrmA enhances survival of Sindbis virus-infected mice. (A) Percent survival of mice infected with the indicated recombinant viruses was determined in four independent experiments with approximately 40 mice (total) per virus. A P value of <0.002 was obtained by life table analysis. (B) Replication of recombinant viruses in mouse brains was determined by plaque assay. Each datum point represents the geometric mean virus titer ± the standard error of the mean (SEM) of values for three mouse brains.