Table II.

Difference in Venous Clinical Severity Scores (VCSS) between patients with combined reflux in the great saphenous vein (GSV) and the saphenofemoral junction (SFJ) vs those with isolated reflux in the GSV

Analysis	Number of patients	Difference in VCSS (with GSV + SFJ reflux vs GSV reflux alone)		95% confidence interval		P-value	Interpretation
		Difference	SE	Low	High		Differencec	Equivalentd
Crudea	352	−0.21	0.26	−0.73	0.30	.42	Not significant	Yes
Adjustedb	346	−0.35	0.28	−0.89	0.19	.20	Not significant	Yes

^aCrude: VCSS score = f(SFJ reflux).

^bAdjusted: VCSS score = f(SFJ reflux, age, sex, race, ethnicity, body mass index).

^cA difference is significant if the confidence interval excludes 0 (ie, P < .05).

^dA difference is equivalent if the 95% confidence interval excludes both −1 and +1.