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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: Oral Oncol. 2024 Jan 26;150:106705. doi: 10.1016/j.oraloncology.2024.106705

Figure 3 – Peripheral G-CSF and neutrophilic cells return to baseline after primary tumor resection.

Figure 3 –

A, illustration of the experiment designed to measure differences in the blood and spleens of tumor bearing or tumor resected mice.

B, a connected-line dot plot shows plasma G-CSF concentrations in tumor bearing or tumor resected mice. The black arrow indicates the time of primary tumor resection (day 20). The G-CSF concentration in mice without tumors is shown as a dotted line.

Connected-line dot plots show the quantification of Ly6G+ cells as a percentage of live total leukocytes in the spleens (C) or blood (D) of tumor bearing or tumor resected mice (n=10 mice total from two independent experiments for each condition and each timepoint). The black arrow indicates the time of primary tumor resection (day 20). The percentage of Ly6G+ cells in mice without tumors is shown as a dotted line in each plot.

For B, C and D, *, P<0.05; **, P<0.01, ***, P<0.001; significance was determined using multiple unpaired t-tests with each timepoint considered independently.