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. Author manuscript; available in PMC: 2024 Mar 14.
Published in final edited form as: J Allergy Clin Immunol. 2023 Nov 7;153(3):809–820. doi: 10.1016/j.jaci.2023.10.023

FIG 5.

FIG 5.

TNFRSF21 expression in airway epithelial cells (AECs) in individuals with AA and AC. Uniform manifold approximation and projection (UMAP) of 20,410 AECs from a publicly available database in (A) with 14 AEC subclusters obtained from endobronchial brush sampling of third-to fourth-generation airway segments from patients with AA and ACs before and 24 hours after segmental allergen challenge. Feature plots in (B) AA (red) and (C) AC (blue) using pseudocoloring to depict TNFRSF21 expression at baseline and after allergen challenge. Cell number and percentages (%) represent gene expression across all AEC subclusters and scaled gene expression in log(CPM).