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. 2023 May 22;42(3):498–509. doi: 10.1038/s41587-023-01791-y

Extended Data Fig. 3. mitoABEMutH un-enable efficient editing on non-GATC sites.

Extended Data Fig. 3

The editing efficiencies of target regions at the 5’-GATA-3’ (a), 5’-GATG-3’ (b) and 5’-GATT-3’ (c) positions with different mitoABEMutH orientations and distances to 5’-GATD-3’. a-c, the mean values from n = 3 biologically independent replicates are shown. In a-c, the purple rounded rectangle represents MutH, and the gray rectangle represents TALE.