Table 1.
The expression and clinicopathological features of SPHK1 and TRAF6 in human CRC tissues.
| SPHK1 expression | TRAF6 expression | ||||||
|---|---|---|---|---|---|---|---|
| Pathologic feature | N | Low | High | P | Low | High | P |
| Infiltration depth | |||||||
| Mucosa and superficial muscular layer | 18 | 5 | 13 | 0.536 | 4 | 14 | 0.751 |
| Deep muscular layer and below | 72 | 15 | 57 | 14 | 58 | ||
| Sex | |||||||
| Male | 50 | 7 | 43 | 0.036 | 9 | 41 | 0.596 |
| Female | 40 | 13 | 27 | 9 | 31 | ||
| TNM staging | |||||||
| I+II stage | 50 | 8 | 42 | 0.112 | 7 | 43 | 0.112 |
| III+IV stage | 40 | 12 | 28 | 11 | 29 | ||
| Lymphatic metastasis | |||||||
| − | 63 | 12 | 51 | 0.268 | 13 | 50 | 0.818 |
| + | 27 | 8 | 19 | 5 | 22 | ||
| Distant metastasis | |||||||
| − | 77 | 14 | 63 | 0.035 | 12 | 65 | 0.020 |
| + | 13 | 6 | 7 | 6 | 7 | ||