Fig. 6. Allogeneic HIP islets achieve long-term survival.

a, Immunofluorescence pictures of dissociated and reaggregated wt^allo and HIP^allo islets from rhesus monkeys (representative images). b, In vitro insulin secretion of wt^allo and HIP^allo islets (mean ± s.d., triplicates). c, The composition of wt^allo and HIP^allo islets of α, β, δ and other cells (mean, triplicates). d, Flow cytometry histograms for HLA class I and II and rhesus CD47 on wt^allo and HIP^allo islets (representative images). e–h, The survival of FLuc⁺ wt^allo and HIP^allo islets in allogeneic rhesus monkeys was followed by BLI (one animal each).