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. 2023 Dec 8;109(4):e1345–e1358. doi: 10.1210/clinem/dgad708

Table 6.

Spearman correlations in 24-hour urine samples in males

Metabolite HbA1c BMI BMI percent BMI-z score BF%
BCAAs mmol/mol Cr, 24 h .265, P = .1736 .149, P = .2517 .234, P = .0721 .234, P = .0713 .231, P = .0779
BCKAs mmol/mol Cr, 24 h .281, P = .1326 .067, P = .6040 .144, P = .2688 .144, P = .2679 .142, P = .2839
KIV mmol/mol Cr, 24 h .312, P = .0928 .148, P = .2508 .219, P = .0896 .219, P = .0894 .204, P = .1212
KMV mmol/mol Cr, 24 h .317, P = .0878 .047, P = .7187 .123, P = .3465 .123, P = .3444 .123, P = .3536
KIC mmol/mol Cr, 24 h .322, P = .0832 .046, P = .7254 .102, P = .4363 .101, P = .4379 .1, P = .4495
Tryptophan mmol/mol Cr, 24 h .37, P = .0440 .176, P = .1707 .242, P = .0606 .243, P = .0588 .285, P = .0289
Kynurenine mmol/mol Cr, 24 h .328, P = .0768 .063, P = .6259 .129, P = .3225 .13, P = .3167 .07, P = .5958
Kynurenic acid mmol/mol Cr, 24 h −.242, P = .1968 −.064, P = .6196 .013, P = .9238 .011, P = .9313 .021, P = .8766
5-HIAA mg/g Cr, 24 h −.341, P = .0654 −.248, P = .0523 −.177, P = .1725 −.177, P = .1731 −.037, P = .7810
Serotonin nmol/mmol Cr, 24 h −.207, P = .2824 −.002, P = .9906 .066, P = .6212 .066, P = .6198 .063, P = .6407
Kynurenine/tryptophan, 24 h .236, P = .2089 −.055, P = .6707 −.029, P = .8233 −.028, P = .8304 −.136, P = .3046
5-HIAA/tryptophan, 24 h −.567, P = .0011 −.315, P = .0126 −.333, P = .0087 −.334, P = .0085 −.285, P = .0284
5-HIAA/kynurenine, 24 h −.484, P = .0067 −.1, P = .4412 −.133, P = .3053 −.135, P = .3011 −.034, P = .7980
Kynurenine/serotonin, 24 h .404, P = .0297 .064, P = .6261 .086, P = .5166 .088, P = .5092 .025, P = .8538
Serotonin/tryptophan, 24 h −.489, P = .0071 −.197, P = .1304 −.185, P = .1609 −.186, P = .1584 −.231, P = .0839

Abbreviations: BCAA, branched-chain amino acid; BCKA, branched-chain ketoacid; BF%, percent body fat; BMI, body mass index; Cr, creatinine; HbA1c, hemoglobin A1c; KIC, α-keto-isocaproate; KIV, α-keto-valerate; KMV, α-keto-β-methylvalerate.