Table 7.
Metabolite | HbA1c | BMI | BMI percent | BMI-z score | BF% |
---|---|---|---|---|---|
BCAAs mmol/mol Cr, 24 h | .456, P = .0013 | .09, P = .4610 | .083, P = .4985 | .078, P = .5259 | .049, P = .6918 |
BCKAs mmol/mol Cr, 24 h | .468, P = .0005 | .105, P = .3757 | .086, P = .4772 | .085, P = .4867 | .124, P = .3104 |
KIV mmol/mol Cr, 24 h | .544, P < .0001 | .213, P = .0704 | .188, P = .1189 | .187, P = .1218 | .2, P = .1002 |
KMV mmol/mol Cr, 24 h | .438, P = .0013 | .087, P = .4636 | .07, P = .5634 | .068, P = .5749 | .108, P = .3771 |
KIC mmol/mol Cr, 24 h | .52, P < .0001 | .111, P = .3482 | .082, P = .5018 | .079, P = .5135 | .127, P = .2995 |
Tryptophan mmol/mol Cr, 24 h | .418, P = .0023 | .077, P = .5184 | .108, P = .3737 | .105, P = .3876 | .035, P = .7737 |
Kynurenine mmol/mol Cr, 24 h | .389, P = .0048 | .217, P = .0647 | .229, P = .0565 | .226, P = .0605 | .155, P = .2048 |
Kynurenic acid mmol/mol Cr, 24 h | −.26, P = .0650 | −.057, P = .6328 | −.074, P = .5450 | −.078, P = .5236 | −.086, P = .4817 |
5-HIAA mg/g Cr, 24 h | .168, P = .2433 | −.24, P = .0426 | −.241, P = .0449 | −.242, P = .0437 | −.289, P = .0162 |
Serotonin nmol/mmol Cr, 24 h | .139, P = .3518 | −.044, P = .7187 | −.006, P = .9605 | −.007, P = .9541 | −.043, P = .7311 |
Kynurenine/tryptophan, 24 h | .166, P = .2453 | .248, P = .0344 | .236, P = .0497 | .234, P = .0509 | .193, P = .1117 |
5-HIAA/tryptophan, 24 h | −.336, P = .0172 | −.29, P = .0134 | −.302, P = .0110 | −.301, P = .0114 | −.264, P = .0281 |
5-HIAA/kynurenine, 24 h | −.363, P = .0096 | −.33, P = .0047 | −.345, P = .0034 | −.344, P = .0036 | −.293, P = .0145 |
Kynurenine/serotonin, 24 h | .498, P = .0004 | .253, P = .0362 | .242, P = .0449 | .239, P = .0481 | .213, P = .0828 |
Serotonin/tryptophan, 24 h | −.413, P = .0039 | −.189, P = .1199 | −.16, P = .1881 | −.156, P = .1995 | −.171, P = .1670 |
Abbreviations: BCAA, branched-chain amino acid; BCKA, branched-chain ketoacid; BF%, percent body fat; BMI, body mass index; Cr, creatinine; HbA1c, hemoglobin A1c; KIC, α-keto-isocaproate; KIV, α-keto-valerate; KMV, α-keto-β-methylvalerate.