Table 11.
Marginal standardized hemoglobin levels after age and sex adjustment or multivariable adjustment among individuals without receiving treatment for anemia
| Marginal standardized hemoglobin levels after age and sex adjustment | ||||
|---|---|---|---|---|
| Categories for estimated glomerular filtration rate (mL/min/1.73 m2) | Albuminuria category | Predicted hemoglobin level (g/dL) | P for interaction | |
| Mean | 95% confidence interval | |||
| <15 | Normoalbuminuria | 12.1 | 11.8–12.4 | <.001 |
| Microalbuminuria | 11.9 | 11.7–12.1 | ||
| Macroalbuminuria | 11.5 | 11.3–11.7 | ||
| 15–<30 | Normoalbuminuria | 12.7 | 12.7–12.8 | <.001 |
| Microalbuminuria | 12.7 | 12.7–12.8 | ||
| Macroalbuminuria | 12.5 | 12.4–12.6 | ||
| 30–<45 | Normoalbuminuria | 13.3 | 13.2–13.3 | .56 |
| Microalbuminuria | 13.3 | 13.3–13.3 | ||
| Macroalbuminuria | 13.3 | 13.2–13.3 | ||
| 45–<60 | Normoalbuminuria | 13.6 | 13.6–13.6 | <.001 |
| Microalbuminuria | 13.6 | 13.6–13.6 | ||
| Macroalbuminuria | 13.6 | 13.6–13.7 | ||
| 60–<90 | Normoalbuminuria | 13.7 | 13.6–13.7 | <.001 |
| Microalbuminuria | 13.8 | 13.7–13.8 | ||
| Macroalbuminuria | 13.8 | 13.8–13.9 | ||
| Marginal standardized hemoglobin levels after multivariable adjustment | ||||
|---|---|---|---|---|
| Categories for estimated glomerular filtration rate (mL/min/1.73 m2) | Albuminuria category | Predicted hemoglobin level (g/dL) | ||
| Mean | 95% confidence interval | P for interaction | ||
| <15 | Normoalbuminuria | 12.4 | 12.1–12.6 | <.001 |
| Microalbuminuria | 12.2 | 12.0–12.3 | ||
| Macroalbuminuria | 11.7 | 11.6–11.9 | ||
| 15–<30 | Normoalbuminuria | 12.9 | 12.8–13.0 | <.001 |
| Microalbuminuria | 12.9 | 12.8–12.9 | ||
| Macroalbuminuria | 12.7 | 12.6–12.8 | ||
| 30–<45 | Normoalbuminuria | 13.3 | 13.3–13.4 | .75 |
| Microalbuminuria | 13.3 | 13.3–13.4 | ||
| Macroalbuminuria | 13.3 | 13.3–13.4 | ||
| 45–<60 | Normoalbuminuria | 13.6 | 13.6–13.6 | <.001 |
| Microalbuminuria | 13.6 | 13.6–13.7 | ||
| Macroalbuminuria | 13.6 | 13.6–13.7 | ||
| 60–<90 | Normoalbuminuria | 13.6 | 13.6–13.7 | <.001 |
| Microalbuminuria | 13.7 | 13.7–13.8 | ||
| Macroalbuminuria | 13.8 | 13.8–13.9 | ||
Differences in estimated glomerular filtration rate among the same estimated glomerular filtration rate category, albuminuria levels, and interaction terms between albuminuria and estimated glomerular filtration rate category were controlled in both models.