Table 15.
HbA1c-stratified marginal standardized prevalence of anemia after multivariable adjustment
| Marginal standardized prevalence of anemia after multivariable adjustment (individuals with HbA1c < 7%) | ||||
|---|---|---|---|---|
| Categories for estimated glomerular filtration rate (mL/min/1.73 m2) | Albuminuria category | Predicted prevalence of anemia | P for interaction | |
| Mean | 95% confidence interval | |||
| <15 | Normoalbuminuria | 0.33 | 0.29–0.37 | <.001 |
| Microalbuminuria | 0.37 | 0.34–0.39 | ||
| Macroalbuminuria | 0.45 | 0.42–0.48 | ||
| 15–<30 | Normoalbuminuria | 0.33 | 0.31–0.35 | <.001 |
| Microalbuminuria | 0.34 | 0.33–0.36 | ||
| Macroalbuminuria | 0.39 | 0.36–0.41 | ||
| 30–<45 | Normoalbuminuria | 0.28 | 0.27–0.29 | <.001 |
| Microalbuminuria | 0.29 | 0.28–0.30 | ||
| Macroalbuminuria | 0.32 | 0.30–0.33 | ||
| 45–<60 | Normoalbuminuria | 0.22 | 0.22–0.23 | <.001 |
| Microalbuminuria | 0.23 | 0.23–0.24 | ||
| Macroalbuminuria | 0.25 | 0.24–0.27 | ||
| 60–<90 | Normoalbuminuria | 0.19 | 0.19–0.20 | .087 |
| Microalbuminuria | 0.20 | 0.19–0.21 | ||
| Macroalbuminuria | 0.21 | 0.19–0.23 | ||
| Marginal standardized prevalence of anemia after multivariable adjustment (individuals with HbA1c ≥ 7%) | ||||
|---|---|---|---|---|
| Categories for estimated glomerular filtration rate (mL/min/1.73 m2) | Albuminuria category | Predicted prevalence of anemia | P for interaction | |
| Mean | 95% confidence interval | |||
| <15 | Normoalbuminuria | 0.32 | 0.25–0.40 | <.001 |
| Microalbuminuria | 0.32 | 0.28–0.37 | ||
| Macroalbuminuria | 0.46 | 0.41–0.52 | ||
| 15–<30 | Normoalbuminuria | 0.29 | 0.27–0.31 | <.001 |
| Microalbuminuria | 0.30 | 0.28–0.31 | ||
| Macroalbuminuria | 0.34 | 0.32–0.36 | ||
| 30–<45 | Normoalbuminuria | 0.25 | 0.24–0.26 | .44 |
| Microalbuminuria | 0.24 | 0.23–0.25 | ||
| Macroalbuminuria | 0.25 | 0.23–0.26 | ||
| 45–<60 | Normoalbuminuria | 0.20 | 0.19–0.20 | .73 |
| Microalbuminuria | 0.19 | 0.19–0.20 | ||
| Macroalbuminuria | 0.19 | 0.18–0.20 | ||
| 60–<90 | Normoalbuminuria | 0.17 | 0.16–0.17 | .43 |
| Microalbuminuria | 0.17 | 0.16–0.17 | ||
| Macroalbuminuria | 0.17 | 0.16–0.18 | ||
Abbreviations: HbA1c, hemoglobin A1c.
Differences in estimated glomerular filtration rate among the same estimated glomerular filtration rate category, albuminuria levels, and interaction terms between albuminuria and estimated glomerular filtration rate category were controlled in both models.