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. 2023 Nov 13;109(4):1012–1032. doi: 10.1210/clinem/dgad660

Table 9.

Marginal standardized hemoglobin levels after age and sex adjustment or multivariable adjustment

Marginal standardized hemoglobin levels after age and sex adjustment
Categories for estimated glomerular filtration rate (mL/min/1.73 m2) Albuminuria category Predicted hemoglobin level (g/dL) P for interaction
Mean 95% confidence interval
<15 Normoalbuminuria 12.0 11.7–12.3 <.001
Microalbuminuria 11.5 11.4–11.7
Macroalbuminuria 11.3 11.2–11.5
15–<30 Normoalbuminuria 12.6 12.5–12.7 <.001
Microalbuminuria 12.6 12.5–12.7
Macroalbuminuria 12.3 12.2–12.4
30–<45 Normoalbuminuria 13.2 13.2–13.2 .17
Microalbuminuria 13.2 13.2–13.2
Macroalbuminuria 13.1 13.1–13.2
45–<60 Normoalbuminuria 13.5 13.5–13.5 .002
Microalbuminuria 13.6 13.5–13.6
Macroalbuminuria 13.5 13.5–13.6
60–<90 Normoalbuminuria 13.6 13.6–13.6 <.001
Microalbuminuria 13.7 13.7–13.7
Macroalbuminuria 13.8 13.7–13.8
Marginal standardized hemoglobin levels after multivariable adjustment
Categories for estimated glomerular filtration rate (mL/min/1.73 m2) Albuminuria category Predicted hemoglobin level (g/dL) P for interaction
Mean 95% confidence interval
<15 Normoalbuminuria 12.4 12.1–12.7 <.001
Microalbuminuria 12.0 11.8–12.1
Macroalbuminuria 11.8 11.7–12.0
15–<30 Normoalbuminuria 12.8 12.7–12.9 <.001
Microalbuminuria 12.8 12.8–12.9
Macroalbuminuria 12.6 12.5–12.6
30–<45 Normoalbuminuria 13.3 13.2–13.3 .50
Microalbuminuria 13.3 13.2–13.3
Macroalbuminuria 13.2 13.2–13.3
45–<60 Normoalbuminuria 13.5 13.5–13.6 .001
Microalbuminuria 13.6 13.6–13.6
Macroalbuminuria 13.6 13.5–13.6
60–<90 Normoalbuminuria 13.6 13.6–13.6 <.001
Microalbuminuria 13.7 13.7–13.7
Macroalbuminuria 13.8 13.7–13.8

Differences in estimated glomerular filtration rate among the same estimated glomerular filtration rate category, albuminuria levels, and interaction terms between albuminuria and estimated glomerular filtration rate category were controlled in both models.