Figure 11.

Photomicrograph of kidney tissue sections from mice of experimental groups. (A,B) Kidney tissue sections from mice of infected animals treated with wheat germ oil (G4) showing (A) tissue cysts contain multiple bradyzoites (arrowheads), aggregated mononuclear cellular inflammatory cells (star). (B) Normal renal tubules (arrowheads), intra-glomerular congestion (arrow). (C,D) Kidney tissue sections from infected animals treated with a combination of propolis + wheat germ oil (G5). (C) Improvement in renal cortical tissue structure: Normal glomerular size and structure (arrow), normal cortical renal tubules (arrow heads), parasitic tissue cyst (circle) and aggregated mononuclear cellular inflammatory cells (star) still present. (D) Mild intertubular congestion in between renal medullary tubules (arrows). Hx&E stain, the bar size was indicated under pictures. (E) Histomorphometry graph showing quantitative and semiquantitative measurements of total lesion scores recorded in kidney tissue sections among the experimental groups. Data are expressed as means ± standard deviations. Significant differences vs. the control group are marked by different asterisks through one-way ANOVA with Tukey’s post-hoc test: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001.