Figure 5.

Photomicrograph of brain cerebral tissue sections from mice of experimental groups. (A,B) Brain tissue sections from infected animals treated with wheat germ oil (G4) showing (A) normal brain structure with normal nerve cells (arrowheads), other areas showing (B) degenerate nerve cells (arrowheads). (C,D) Brain tissue sections from infected animals treated with a combination of propolis + wheat germ oil (G5) marked improvement in histological structure of brain tissue except for presence of mild pericapillary edema (zigzag arrows), mild glia cell reaction (arrowheads), and normal nerve cells (thin arrows). note: absence of bradyzoites or tissue cyst. Hx&E stain, the bar size was indicated under pictures. (E) Histomorphometry graph showing quantitative and semiquantitative measurements of total lesion scores recorded in brain tissue sections among the experimental groups. Data are expressed as means ± standard deviations. Significant differences vs. the control group are marked by different asterisks through one-way ANOVA with Tukey’s post-hoc test: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001.