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Flowchart of the study design. We identified an oncogenic factor, PYGB, in PC by WGCNA and LASSO regression models. PYGB was then found to be highly expressed in almost all tumors by pan-cancer analysis but had the most significant impact on the prognosis of PC. Then, we verified the effects of PYGB on PC’s proliferation, invasion, and metastasis through a series of cell and animal experiments and found the potential oncogenic mechanism of PYGB in PC through enrichment analysis
