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. 2024 Mar 14;150(3):127. doi: 10.1007/s00432-024-05644-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 12 — U0126 inhibited the promotion of PYGB in PC. A–C Colony formation, EdU, and CCK-8 assays demonstrated that U0126 blocked the proliferative ability of PYGB in PC cells. D and E The results of the scratch assay and Transwell assay showed that U0126 successfully inhibited the invasive and metastatic properties conferred by PYGB in PC cells