Table 2.

Transfusion reaction related symptoms in patients receiving pre-storage and post-storage leukoreduced apheresis platelets

	Unmatched			Propensity-score matched
	Post-storage (n = 18,953)	Pre-storage (n = 21,884)	P value*	Post-storage (n = 18,314)	Pre-storage (n = 18,314)	P value*
Chills, n (%)	60 (0.3165)	33 (0.1507)	< 0.001	56 (0.3057)	30 (0.1638)	0.004
Fever, n (%)	43 (0.2268)	24 (0.1096)	0.003	40 (0.2184)	23 (0.1255)	0.032
Itching, n (%)	70 (0.3693)	56 (0.2558)	0.039	65 (0.3549)	54 (0.2948)	0.312
Face flushing, n (%)	22 (0.1160)	17 (0.0776)	0.211	21 (0.1144)	17 (0.0928)	0.515
Urticaria, n (%)	73 (0.3851)	47 (0.2147)	0.001	69 (0.3767)	42 (0.2293)	0.010
Nausea and vomiting, n (%)	7 (0.0369)	4 (0.0182)	0.250	7 (0.0382)	4 (0.0218)	0.368
Dyspnea, n (%)	26 (0.1371)	8 (0.0365)	< 0.001	24 (0.1310)	8 (0.0436)	0.004
Stridor, n (%)	4 (0.0211)	3 (0.0137)	0.568	4 (0.0218)	2 (0.0109)	0.412
Headache, n (%)	1 (0.0052)	0 (0.000)	-	1 (0.0054)	0 (0.000)	-
Hypertension, n (%)	16 (0.0844)	3 (0.0137)	< 0.001	16 (0.0873)	1 (0.0054)	< 0.001
Hypotension, n (%)	9 (0.0474)	6 (0.0274)	0.289	9 (0.0491)	6 (0.0327)	0.441
Syncope, n (%)	1 (0.0052)	1 (0.0045)	0.920	1 (0.0054)	1 (0.0054)	> 0.999
Cold sweating, n (%)	4 (0.0211)	2 (0.091)	0.322	4 (0.2184)	2 (0.0109)	0.412
Pharyngeal edema, n (%)	7 (0.0369)	3 (0.0137)	0.133	7 (0.0382)	3 (0.0163)	0.204
Shock, n (%)	1 (0.0052)	2 (0.0091)	0.652	1 (0.0054)	2 (0.0109)	0.561
Chest pain, n (%)	3 (0.0158)	2 (0.0091)	0.541	3 (0.0163)	2 (0.0109)	0.652
Total, n (%)	347 (1.8308)	211 (0.9641)	< 0.001	328 (1.7909)	197 (1.0756)	< 0.001

^*Estimated by two proportion z-test