TABLE 2.

Central analgesic effect of different doses of the crude methanolic extract of the leaves of C. ovalis in the mice model. Each value is expressed as mean ± SEM (n = 4). *p < 0.05, **p < 0.01, ***p < 0.001 and compared with the control group (only distilled water).

Treatment	% time elongation (mean ± SEM)
	At 30 min	At 60 min	At 90 min
Standard	146.75 ± 0.16	345.66 ± 0.25**	683.12 ± 0.34**
Control	35.67 ± 0.11	24.92 ± 0.64	24.30 ± 0.91
COCME 200	45.34 ± 0.26*	102.92 ± 0.22**	203.14 ± 0.15**
COCME 400	132.58 ± 0.23**	193.92 ± 0.16**	309.37 ± 0.21**
COCME 600	139.75 ± 0.23**	222.34 ± 0.07**	381.14 ± 0.55**