Table 2.

Signaling pathways regulated by miRNAs highly expressed in exosomes from 081010-treated Caco-2 cells

Signaling pathway	KEGG pathway	miRNA	p-value
Insulin signaling	Insulin resistance	1914-5p	0.036
		8089	0.031
		1202	0.043
	Insulin signaling pathway	1914-5p	0.013
		8089	0.001
		1202	0.001
	Pl3K-Akt signaling pathway	1914-5p	0.012
		6829-5p	0.016
		8089	0.016
	FoxO signaling pathway	1914-5p	0.012
Neurotrophin	Neurotrophin signaling pathway	6829-5p	0.026
		8089	0.026
		1202	0.023
Cardiac muscle	Adrenergic signaling in cardiomyocytes	1202	0.008
	Arrhythmogenic right ventricular cardiomyopathy	8089	0.001
	Hypertrophic cardiomyopathy	8089	0.006
		1202	0.036
	Dilated cardiomyopathy	8089	0.011
	Vascular smooth muscle contraction	1202	0.043
Longevity	Longevity regulating pathway	1914-5p	0.002
		1202	0.038
	Longevity regulating pathway-multiple species	1914_5p	0.036
		1202	0.045
	mTOR signaling pathway	1914-5p	0.000
	Autophagy-animal	1914-5p	0.019