Table 2.

Positive lifestyle changes in 2001–2004 (prior to diagnosis), 2004–2007 (around diagnosis) and 2007–2010 (following diagnosis)-in women who were and were not diagnosed with OA between 2004 and 2007.

Lifestyle change	Women diagnosed with OA		Women not diagnosed with OA		p-value	OR (95% CI)c	p-value for interaction of OA with time
	N	% who made a positive change	N	% who made a positive change
Weight loss (≥ 5 kg)
Period prior to OA diagnosis (2001–04)	517	10.1	3342	10.1	0.95	0.98 (0.92, 1.04)	0.04
Period around OA diagnosis (2004–07)	538	13.0	3452	11.4	0.26	1.00 (0.94, 1.06)
Period following OA diagnosis (2007–10)	564	14.4	3700	9.8	< 0.001	1.05 (0.99, 1.10)
Total sitting time (reduce > 1 h/day)
Period prior to OA diagnosis	523	34.6	3266	24.9	< 0.001	1.09 (1.05, 1.14)	0.61
Period around OA diagnosis	467	36.4	3209	24.5	< 0.001	1.11 (1.06, 1.16)
Period following OA diagnosis	542	39.1	3386	29.5	< 0.001	1.07 (1.03, 1.11)
Increase in PA (increase > 150 MET.min/week)
Period prior to OA diagnosis	518	50.8	3406	48.1	0.25	1.02 (0.98, 1.06)	0.22
Period around OA diagnosis	510	40.8	3347	43.8	0.20	0.98 (0.94, 1.02)
Period following OA diagnosis	522	38.5	3479	40.3	0.43	0.99 (0.95, 1.03)
Stopped smokinga
Period prior to OA diagnosis	85	78.8	435	16.1	< 0.001	1.86 (1.64, 2.10)	0.32
Period around OA diagnosis	73	83.6	406	26.4	< 0.001	1.72 (1.53, 1.94)
Period following OA diagnosis	70	88.6	335	17.9	< 0.001	1.81 (1.60, 2.05)
Reduction in alcoholb
Period prior to OA diagnosis	32	28.1	181	30.4	0.80	0.98 (0.82, 1.17)	0.37
Period around OA diagnosis	34	38.2	261	41.0	0.76	0.97 (0.83, 1.14)
Period following OA diagnosis	36	22.2	258	36.4	0.09	0.86 (0.72, 1.02)

^aExcludes all ex- and non-smokers.

^bExcludes all non-risky alcohol drinkers.

^cOdds ratio adjusted for chronic diseases, depressive symptoms, pain, physical function, menopausal status, OR (95% CI) is the odds in the OA group versus the No-OA group.