Table 2.

Volumetric correlations with LLD clinical outcomes.

	Age	GDS	MADRS	MMSE	RAVLT-IR
VOI	r, P	r, P	r, P	r, P	r, P
Hippocampus	−0.47, 0.02	0.21, 0.35	0.28, 0.19	−0.32, 0.13	−0.31, 0.19
Mesotemporal	−0.42, 0.04	0.07, 0.76	0.12, 0.60	−0.16, 0.47	0.07, 0.77
Anterior cingulate	−0.17, 0.42	0.24, 0.27	0.33, 0.13	−0.26, 0.23	0.08, 0.73
Lateral temporal	−0.39, 0.06	0.04, 0.87	0.14, 0.52	−0.13, 0.54	0.09, 0.72
Prefrontal	−0.13, 0.55	−0.16, 0.46	−0.06, 0.80	0.28, 0.20	0.56, 0.01
Parietal	−0.62, 0.001*	0.45, 0.03	0.44, 0.03	−0.45, 0.03	−0.12, 0.61

VOI volume of interest, GDS Geriatric Depression Scale, MADRS Montgomery–Asberg depression rating scale, MMSE Mini-Mental State Examination, RAVLT-IR Rey Auditory Verbal Learning Test immediate recall trials, r Pearson’s r. P P value.

P values below 0.05 are indicated in bold.

*Significant values after Bonferroni correction (p < 0.008).