Fig. 2. Schisandra chinensis extract increases low-density lipoprotein receptor (LDLR) expression and inhibits proprotein convertase subtilisin/kexin 9 (PCSK9) secretion in delipidated serum (DLPS)-induced lipid-deprived conditions.
Cell viability (A) LDLR protein expression in HepG2 cells (B) and PCSK9 levels in the media (C). The results are expressed as the mean ± SEM. # indicates a significant difference compared to the normal control (#p < 0.05, ##p < 0.01, ###p < 0.001). * indicates a significant difference compared to DLPS-treated HepG2 cells (*p < 0.05, **p < 0.01, ***p < 0.001). FBS, fetal bovine serum; SCE, Schisandra chinensis extract.
