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. 1998 Jan;72(1):558–563. doi: 10.1128/jvi.72.1.558-563.1998

TABLE 2.

Tumor induction by virus with S257C mutationa

Characteristic PTA with S257C mutation PTA
No. of mice with tumors/total no. of mice 48/48 256/259
Mean age (days) at necropsy (range) 83 (53–227) 108 (43–381)
No. of epithelial tumors (%)
 Hair follicle 40 (83) 229 (88)
 Thymus 33 (69) 227 (88)
 Mammary gland 23 (48) 126 (49)
 Salivary gland 0 (0) 148 (57)
No. of mesenchymal tumors (%)
 Kidney 17 (35) 123 (47)
 Bone 12 (25) 58 (22)
 Subcutaneous connective tissue 2 (4) 56 (22)
a

Tumor profiles were carried out as previously described (27); data for the wild-type strain were previously reported (27).