Table 3.

Chi-Square Test for Comparison of Prevalence of Treatment With Antidepressants in Glioma Cases and Matched Controls Without Glioma

Treatment	Cases, n (%)a	Controls, n (%)	P value
All antidepressants	340 (27)	965 (16)	< .001
Selective serotonin reuptake inhibitor (SSRI)	225 (18)	638 (10)	< .001
Non-SSRI	166 (13)	506 (8)	< .001

^aPrevalence of antidepressant medication among total cases and controls.

Due to matching of glioma cases and controls without glioma based on time, the number of cases is 340 patients in this analysis compared to that of the whole cohort presented in Table 1 (n = 346).