Table 4.
Uni- and Multivariable Cox Proportional Hazards Models Showing Hazard Ratio for Death in Glioma Patients Receiving Selective Serotonin Reuptake Inhibitor (SSRI) or Non-SSRI Treatment With Glioma Patients Without Antidepressants As a Reference
| Univariable | Multivariable | ||||||
|---|---|---|---|---|---|---|---|
| Treatment | Grade | HR | CI | P value | HR | CI | P value |
| SSRI | Grade 4 | 3.45 | 2.79–4.26 | < .001 | 3.32 | 2.69–4.10 | < .001 |
| Grade 2-3 | 5.15 | 3.49–7.61 | < .001 | 3.26 | 2.19–4.85 | < .001 | |
| Non-SSRI | Grade 4 | 3.29 | 2.34–4.62 | < .001 | 3.54 | 2.52–4.99 | < .001 |
| Grade 2-3 | 4.41 | 2.42–8.03 | < .001 | 7.71 | 4.22–14.12 | < .001 | |