Table 6.

Performance comparison of CALIBER and methods for Conformational epitopes: BepiPred-3.0, Epitope3D, Seppa-3.0, Discotope-2.0, and Ellipro, on the blind test set Epitope3D, on residues with RSA above 15%.

Method	AUC	BAC	MCC
CALIBER-Boosting,ESM IF1	0.7	0.63	0.15
BepiPred-3.0	0.67	0.63	0.16
Epitope3D	0.59	0.61	0.45
Seppa-3.0	0.55	0.52	0.02
Discotope-2.0	0.51	0.5	-0.01
Ellipro	0.49	0.44	-0.06